Optimising Cancer Vaccine Design in Sarcoma
نویسندگان
چکیده
منابع مشابه
Design of a MUC1-based cancer vaccine.
The epithelial type 1 transmembrane mucin MUC1 is long-established as a marker for monitoring recurrence of breast cancer, and beyond its diagnostic marker qualities, it is a promising target for immunotherapeutic strategies to treat cancer by active specific immunization. The mucin is able to break tolerance and to induce humoral immune responses in healthy subjects and in cancer patients, but...
متن کاملImmunoinformatics Design of a Multi-epitope-based Vaccine Against Colorectal Cancer
Background: Bioinformatic approaches for designing vaccines have become a promising alternative to conventional methods. We herein designed a multi-epitope-based vaccine against colorectal cancer (CRC). Methods: Used peptides in the CRC vaccines were retrieved from databases of PubMed, Web of Science, Google Scholar, and Clinical trials. The adjuvants of Mycobacterial heparin-binding hemagglut...
متن کاملDesign of a Novel Recombinant Multi-Epitope Vaccine against Triple-Negative Breast Cancer
Background: Triple-negative breast cancer (TNBC) is determined by the absence of ERBB2, estrogen and progesterone receptors’ expression. Cancer vaccines, as the novel immunotherapy strategies, have emerged as promising tools for treating the advanced stage of TNBC. The aim of this study was to evaluate Carcinoembryonic antigen (CEA), Metadherin (MTDH), and Mucin 1 (MUC-1) proteins as vaccine ...
متن کاملOptimising a handcrafted dialogue system design
In the Spoken Dialogue System literature, all studies consider the dialogue move as the unquestionable unit for reinforcement learning. Rather than learning at the dialogue move level, we apply the learning at the design level for three reasons : 1/ to alleviate the high-skill prerequisite for developers, 2/ to reduce the learning complexity by taking into account just the relevant subset of th...
متن کاملOptimising Cancer Immunotherapy: Challenges and Opportunities
1. prIME Oncology, Atlanta, Georgia, USA 2. prIME Oncology, The Hague, Netherlands; University of Sheffield, Weston Park Hospital, Sheffield, UK 3. Gustave Roussy, Villejuif, France 4. Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain 5. Erasmus Medical Center Cancer Institute, Rotterdam, Netherlands 6. Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy 7. Ludwig Center...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancers
سال: 2018
ISSN: 2072-6694
DOI: 10.3390/cancers11010001